Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation SB Rothbart, BM Dickson, MS Ong, K Krajewski, S Houliston, DB Kireev, ... Genes and Development 27 (11), 1288-1298, 2013 | 193 | 2013 |
An interactive database for the assessment of histone antibody specificity SB Rothbart, BM Dickson, JR Raab, AT Grzybowski, K Krajewski, AH Guo, ... Molecular cell 59 (3), 502-511, 2015 | 177 | 2015 |
A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1 JI Stuckey, BM Dickson, N Cheng, Y Liu, JL Norris, SH Cholensky, ... Nature chemical biology 12 (3), 180-187, 2016 | 167 | 2016 |
Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1 JS Harrison, EM Cornett, D Goldfarb, PA DaRosa, ZM Li, F Yan, ... Elife 5, e17101, 2016 | 140 | 2016 |
Examining the roles of H3K4 methylation states with systematically characterized antibodies RN Shah, AT Grzybowski, EM Cornett, AL Johnstone, BM Dickson, ... Molecular cell 72 (1), 162-177. e7, 2018 | 114 | 2018 |
Free energy calculations: An efficient adaptive biasing potential method BM Dickson, F Legoll, T Lelievre, G Stoltz, P Fleurat-Lessard The Journal of Physical Chemistry B 114 (17), 5823-5830, 2010 | 81 | 2010 |
The structural basis of the dominant negative phenotype of the Gαi1β1γ2 G203A/A326S heterotrimer P Liu, M Jia, XE Zhou, PW De Waal, BM Dickson, B Liu, L Hou, Y Yin, ... Acta Pharmacologica Sinica 37 (9), 1259-1272, 2016 | 61 | 2016 |
Identification of a Fragment-like Small Molecule Ligand for the Methyl-lysine Binding Protein, 53BP1 et al MT Perfetti, BM Baughman, BM Dickson ACS Chemical Biology, 2015 | 56 | 2015 |
αC helix as a switch in the conformational transition of Src/CDK-like kinase domains H Huang, R Zhao, BM Dickson, RD Skeel, CB Post The Journal of Physical Chemistry B 116 (15), 4465-4475, 2012 | 51 | 2012 |
Molecular mechanisms of fentanyl mediated β-arrestin biased signaling PW De Waal, J Shi, E You, X Wang, K Melcher, Y Jiang, HE Xu, ... PLoS computational biology 16 (4), e1007394, 2020 | 48 | 2020 |
Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1 RM Vaughan, BM Dickson, MF Whelihan, AL Johnstone, EM Cornett, ... Proceedings of the National Academy of Sciences 115 (35), 8775-8780, 2018 | 40 | 2018 |
Structure–activity relationships and kinetic studies of peptidic antagonists of CBX chromodomains JI Stuckey, C Simpson, JL Norris-Drouin, SH Cholensky, J Lee, R Pasca, ... Journal of medicinal chemistry 59 (19), 8913-8923, 2016 | 39 | 2016 |
Approaching a parameter-free metadynamics BM Dickson Physical Review E 84 (037701), 2011 | 37 | 2011 |
Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance RM Vaughan, BM Dickson, EM Cornett, JS Harrison, B Kuhlman, ... Nucleic acids research 46 (9), 4405-4416, 2018 | 35 | 2018 |
Ketolysis drives CD8+ T cell effector function through effects on histone acetylation KM Luda, J Longo, SM Kitchen-Goosen, LR Duimstra, EH Ma, ... Immunity 56 (9), 2021-2035. e8, 2023 | 31 | 2023 |
Unrestrained computation of free energy along a path BM Dickson, H Huang, CB Post The Journal of Physical Chemistry B 116 (36), 11046-11055, 2012 | 31 | 2012 |
Parallel replica dynamics with a heterogeneous distribution of barriers: Application to n-hexadecane pyrolysis O Kum, BM Dickson, SJ Stuart, BP Uberuaga, AF Voter The Journal of chemical physics 121 (20), 9808-9819, 2004 | 31 | 2004 |
A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity EM Cornett, BM Dickson, K Krajewski, N Spellmon, A Umstead, ... Science advances 4 (11), eaav2623, 2018 | 30 | 2018 |
The structure–activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface MA Camerino, N Zhong, A Dong, BM Dickson, LI James, BM Baughman, ... Medchemcomm 4 (11), 1501-1507, 2013 | 29 | 2013 |
Quantitative characterization of bivalent probes for a dual bromodomain protein, transcription initiation factor TFIID subunit 1 JL Suh, B Watts, JI Stuckey, JL Norris-Drouin, SH Cholensky, BM Dickson, ... Biochemistry 57 (14), 2140-2149, 2018 | 23 | 2018 |