The genetic landscape of a cell M Costanzo, A Baryshnikova, J Bellay, Y Kim, ED Spear, CS Sevier, ... science 327 (5964), 425-431, 2010 | 2554 | 2010 |
A global genetic interaction network maps a wiring diagram of cellular function M Costanzo, B VanderSluis, EN Koch, A Baryshnikova, C Pons, G Tan, ... Science 353 (6306), aaf1420, 2016 | 1343 | 2016 |
Systematic analysis of complex genetic interactions E Kuzmin, B VanderSluis, W Wang, G Tan, R Deshpande, Y Chen, M Usaj, ... Science 360 (6386), eaao1729, 2018 | 295 | 2018 |
Forazoline A: marine‐derived polyketide with antifungal in vivo efficacy TP Wyche, JS Piotrowski, Y Hou, D Braun, R Deshpande, S McIlwain, ... Angewandte Chemie International Edition 53 (43), 11583-11586, 2014 | 118 | 2014 |
Plant-derived antifungal agent poacic acid targets β-1, 3-glucan JS Piotrowski, H Okada, F Lu, SC Li, L Hinchman, A Ranjan, DL Smith, ... Proceedings of the National Academy of Sciences 112 (12), E1490-E1497, 2015 | 111 | 2015 |
Functional annotation of chemical libraries across diverse biological processes JS Piotrowski, SC Li, R Deshpande, SW Simpkins, J Nelson, Y Yashiroda, ... Nature Chemical Biology 13 (9), 982-993, 2017 | 94 | 2017 |
Unraveling the biology of a fungal meningitis pathogen using chemical genetics JCS Brown, J Nelson, B VanderSluis, R Deshpande, A Butts, S Kagan, ... Cell 159 (5), 1168-1187, 2014 | 92 | 2014 |
Profiling bortezomib resistance identifies secondary therapies in a mouse myeloma model HAF Stessman, LB Baughn, A Sarver, T Xia, R Deshpande, A Mansoor, ... Molecular cancer therapeutics 12 (6), 1140-1150, 2013 | 92 | 2013 |
A comparative genomic approach for identifying synthetic lethal interactions in human cancer R Deshpande, MK Asiedu, M Klebig, S Sutor, E Kuzmin, J Nelson, ... Cancer research 73 (20), 6128-6136, 2013 | 73 | 2013 |
Conserved rules govern genetic interaction degree across species EN Koch, M Costanzo, J Bellay, R Deshpande, K Chatfield-Reed, G Chua, ... Genome biology 13, 1-15, 2012 | 70 | 2012 |
Padanamides A and B, Highly Modified Linear Tetrapeptides Produced in Culture by a Streptomyces sp. Isolated from a Marine Sediment DE Williams, DS Dalisay, BO Patrick, T Matainaho, K Andrusiak, ... Organic letters 13 (15), 3936-3939, 2011 | 60 | 2011 |
Chemical genomic profiling via barcode sequencing to predict compound mode of action JS Piotrowski, SW Simpkins, SC Li, R Deshpande, SJ McIlwain, IM Ong, ... Chemical Biology: Methods and Protocols, 299-318, 2015 | 45 | 2015 |
Comparison of profile similarity measures for genetic interaction networks R Deshpande, B VanderSluis, CL Myers PloS one 8 (7), e68664, 2013 | 45 | 2013 |
Unbiased screening of marine sponge extracts for anti-inflammatory agents combined with chemical genomics identifies girolline as an inhibitor of protein synthesis SY Fung, V Sofiyev, J Schneiderman, AF Hirschfeld, RE Victor, K Woods, ... ACS chemical biology 9 (1), 247-257, 2014 | 40 | 2014 |
A scalable approach for discovering conserved active subnetworks across species R Deshpande, S Sharma, CM Verfaillie, WS Hu, CL Myers PLoS computational biology 6 (12), e1001028, 2010 | 33 | 2010 |
Using BEAN-counter to quantify genetic interactions from multiplexed barcode sequencing experiments SW Simpkins, R Deshpande, J Nelson, SC Li, JS Piotrowski, HN Ward, ... Nature protocols 14 (2), 415-440, 2019 | 25 | 2019 |
A general biological simulator: the multiscale object oriented simulation environment, MOOSE S Ray, R Deshpande, N Dudani, US Bhalla BMC Neuroscience 9, 1-2, 2008 | 24 | 2008 |
Predicting bioprocess targets of chemical compounds through integration of chemical-genetic and genetic interactions SW Simpkins, J Nelson, R Deshpande, SC Li, JS Piotrowski, EH Wilson, ... PLoS computational biology 14 (10), e1006532, 2018 | 21* | 2018 |
Efficient strategies for screening large-scale genetic interaction networks R Deshpande, J Nelson, SW Simpkins, M Costanzo, JS Piotrowski, SC Li, ... BioRxiv, 159632, 2017 | 10 | 2017 |
Systematic identification of pleiotropic genes from genetic interactions EN Koch, M Costanzo, R Deshpande, B Andrews, C Boone, CL Myers BioRxiv, 112326, 2017 | 3 | 2017 |