David Alexander Brown
David Alexander Brown
The Westmead Institute for Medical Research, University of Sydney
Verified email at - Homepage
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GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation
J Xu, TR Kimball, JN Lorenz, DA Brown, AR Bauskin, R Klevitsky, ...
Circulation research 98 (3), 342-350, 2006
Tumor-induced anorexia and weight loss are mediated by the TGF-β superfamily cytokine MIC-1
H Johnen, S Lin, T Kuffner, DA Brown, VWW Tsai, AR Bauskin, L Wu, ...
Nature medicine 13 (11), 1333-1340, 2007
Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum
JB Welsh, LM Sapinoso, SG Kern, DA Brown, T Liu, AR Bauskin, RL Ward, ...
Proceedings of the National Academy of Sciences 100 (6), 3410-3415, 2003
Concentration in plasma of macrophage inhibitory cytokine-1 and risk of cardiovascular events in women: a nested case-control study
DA Brown, SN Breit, J Buring, WD Fairlie, AR Bauskin, T Liu, PM Ridker
The Lancet 359 (9324), 2159-2163, 2002
Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers
J Koopmann, P Buckhaults, DA Brown, ML Zahurak, N Sato, N Fukushima, ...
Clinical Cancer Research 10 (7), 2386-2392, 2004
Role of macrophage inhibitory cytokine-1 in tumorigenesis and diagnosis of cancer
AR Bauskin, DA Brown, T Kuffner, H Johnen, XW Luo, M Hunter, SN Breit
Cancer research 66 (10), 4983-4986, 2006
MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma
DA Brown, RL Ward, P Buckhaults, T Liu, KE Romans, NJ Hawkins, ...
Clinical Cancer Research 9 (7), 2642-2650, 2003
Serum markers in patients with resectable pancreatic adenocarcinoma: macrophage inhibitory cytokine 1 versus CA19-9
J Koopmann, CNW Rosenzweig, Z Zhang, MI Canto, DA Brown, M Hunter, ...
Clinical Cancer Research 12 (2), 442-446, 2006
The MIC-1/GDF15-GFRAL Pathway in Energy Homeostasis: Implications for Obesity, Cachexia, and Other Associated Diseases
VWW Tsai, Y Husaini, A Sainsbury, DA Brown, SN Breit
Cell metabolism 28 (3), 353-368, 2018
Autoimmune psychosis: an international consensus on an approach to the diagnosis and management of psychosis of suspected autoimmune origin
TA Pollak, BR Lennox, S Müller, ME Benros, H Prüss, LT van Elst, H Klein, ...
The Lancet Psychiatry 7 (1), 93-108, 2020
Macrophage inhibitory cytokine‐1 (MIC‐1/GDF15): a new marker of all‐cause mortality
FE Wiklund, AM Bennet, PKE Magnusson, UK Eriksson, F Lindmark, L Wu, ...
Aging cell 9 (6), 1057-1064, 2010
The TGF-β superfamily cytokine, MIC-1/GDF15: a pleotrophic cytokine with roles in inflammation, cancer and metabolism
SN Breit, H Johnen, AD Cook, VWW Tsai, MG Mohammad, T Kuffner, ...
Growth factors 29 (5), 187-195, 2011
The transforming growth factor-β superfamily cytokine macrophage inhibitory cytokine-1 is present in high concentrations in the serum of pregnant women
AG Moore, DA Brown, WD Fairlie, AR Bauskin, PK Brown, MLC Munier, ...
The Journal of Clinical Endocrinology & Metabolism 85 (12), 4781-4788, 2000
Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells
T Liu, AR Bauskin, J Zaunders, DA Brown, S Pankurst, PJ Russell, ...
Cancer research 63 (16), 5034-5040, 2003
Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitis
DA Brown, PE Sawchenko
Journal of Comparative Neurology 502 (2), 236-260, 2007
Macrophage inhibitory cytokine-1: a novel biomarker for p53 pathway activation
H Yang, Z Filipovic, D Brown, SN Breit, LT Vassilev
Molecular Cancer Therapeutics 2 (10), 1023-1029, 2003
TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator
VWW Tsai, L Macia, H Johnen, T Kuffner, R Manadhar, SB Jørgensen, ...
PloS one 8 (2), e55174, 2013
Macrophage inhibitory cytokine 1 (MIC-1/GDF15) decreases food intake, body weight and improves glucose tolerance in mice on normal & obesogenic diets
L Macia, VWW Tsai, AD Nguyen, H Johnen, T Kuffner, YC Shi, S Lin, ...
PloS one 7 (4), e34868, 2012
Macrophage inhibitory cytokine 1: a new prognostic marker in prostate cancer
DA Brown, F Lindmark, P Stattin, K Bälter, HO Adami, SL Zheng, J Xu, ...
Clinical cancer research 15 (21), 6658-6664, 2009
The propeptide mediates formation of stromal stores of PROMIC-1: role in determining prostate cancer outcome
AR Bauskin, DA Brown, S Junankar, KK Rasiah, S Eggleton, M Hunter, ...
Cancer research 65 (6), 2330-2336, 2005
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