Expression of pro-and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors DG Nowak, J Woolard, EM Amin, O Konopatskaya, MA Saleem, ... Journal of Cell Science 121 (20), 3487-3495, 2008 | 430 | 2008 |
WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing EM Amin, S Oltean, J Hua, MVR Gammons, M Hamdollah-Zadeh, ... Cancer Cell 20 (6), 768-780, 2011 | 281 | 2011 |
Regulation of vascular endothelial growth factor (VEGF) splicing from pro-angiogenic to anti-angiogenic isoforms a novel therapeutic strategy for angiogenesis DG Nowak, EM Amin, ES Rennel, C Hoareau-Aveilla, M Gammons, ... Journal of Biological Chemistry 285 (8), 5532-5540, 2010 | 277 | 2010 |
Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression M Chen, CP Pratt, ME Zeeman, N Schultz, BS Taylor, A O'Neill, ... Cancer Cell 20 (2), 173-186, 2011 | 185 | 2011 |
Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization S Senturk, NH Shirole, DG Nowak, V Corbo, A Vaughan, DA Tuveson, ... Nature Communications 8, doi:10.1038/ncomms14370, 2017 | 170 | 2017 |
Myc drives Pten/ p53-deficient proliferation and metastasis due to Il6-secretion and Akt-suppression via Phlpp2. DG Nowak, H Cho, T Herzka, K Watrud, DV DeMarco, VM Wang, ... Cancer Discovery, 2015 | 84 | 2015 |
Overexpression of VEGF165b in podocytes reduces glomerular permeability Y Qiu, J Ferguson, S Oltean, CR Neal, A Kaura, H Bevan, E Wood, ... Journal of the American Society of Nephrology 21 (9), 1498-1509, 2010 | 47 | 2010 |
The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein M Chen, DG Nowak, N Narula, B Robinson, K Watrud, A Ambrico, ... Journal of Cell Biology 216 (3), 641-656, 2017 | 45 | 2017 |
The PHLPP2 phosphatase is a druggable driver of prostate cancer progression DG Nowak, KC Katsenelson, KE Watrud, M Chen, G Mathew, ... Journal of Cell Biol 218 (6), 1943-1957, 2019 | 40 | 2019 |
Utility of single cell genomics in diagnostic evaluation of prostate cancer J Alexander, J Kendall, J McIndoo, L Rodgers, R Aboukhalil, D Levy, ... Cancer Research, 2017 | 34 | 2017 |
Molecular pathways: PI3K pathway phosphatases as biomarkers for cancer prognosis and therapy M Chen, DG Nowak, LC Trotman Clinical Cancer Research 20 (12), 3057-3063, 2014 | 34 | 2014 |
Borrelidin modulates the alternative splicing of VEGF in favour of anti-angiogenic isoforms J Woolard, W Vousden, SJ Moss, A Krishnakumar, MVR Gammons, ... Chemical Science 2 (2), 273-278, 2011 | 34 | 2011 |
Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output G Reyes, M Niederst, K Cohen-Katsenelson, JD Stender, MT Kunkel, ... Proceedings of the National Academy of Sciences 111 (38), E3957-E3965, 2014 | 33 | 2014 |
Prostate cancer genetic-susceptibility locus on chromosome 20q13 is amplified and coupled to androgen receptor-regulation in metastatic tumors DP Labbé, DG Nowak, G Deblois, L Lessard, V Giguère, LC Trotman, ... Molecular Cancer Research 12 (2), 184-189, 2014 | 13 | 2014 |
Combined whole-organ imaging at single-cell resolution and immunohistochemical analysis of prostate cancer and its liver and brain metastases J Taranda, G Mathew, K Watrud, N El-Amine, MF Lee, C Elowsky, ... Cell reports 37 (7), 2021 | 6 | 2021 |
Novel genetically engineered mouse models for clear cell renal cell carcinoma JC van der Mijn, KB Laursen, L Fu, F Khani, LE Dow, DG Nowak, Q Chen, ... Scientific Reports 13 (1), 8246, 2023 | 3 | 2023 |