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Sebastian Hoffmann
Sebastian Hoffmann
seh consulting + services
Verified email at seh-cs.com
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Year
A modular approach to the ECVAM principles on test validity
T Hartung, S Bremer, S Casati, S Coecke, R Corvi, S Fortaner, L Gribaldo, ...
Alternatives to Laboratory Animals 32 (5), 467-472, 2004
3702004
“ToxRTool”, a new tool to assess the reliability of toxicological data
K Schneider, M Schwarz, I Burkholder, A Kopp-Schneider, L Edler, ...
Toxicology letters 189 (2), 138-144, 2009
3272009
A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing
D Basketter, H Clewell, I Kimber, A Rossi, B Blaauboer, R Burrier, ...
2512012
The ECVAM international validation study on in vitro tests for acute skin irritation: report on the validity of the EPISKIN and EpiDerm assays and on the Skin Integrity …
H Spielmann, S Hoffmann, M Liebsch, P Botham, JH Fentem, C Eskes, ...
Alternatives to laboratory animals 35 (6), 559-601, 2007
2482007
International validation of novel pyrogen tests based on human monocytoid cells
S Hoffmann, A Peterbauer, S Schindler, S Fennrich, S Poole, Y Mistry, ...
Journal of immunological methods 298 (1-2), 161-173, 2005
2342005
Categorization of chemicals according to their relative human skin sensitizing potency
DA Basketter, N Alépée, T Ashikaga, J Barroso, N Gilmour, C Goebel, ...
Dermatitis 25 (1), 11-21, 2014
2152014
A proposed eye irritation testing strategy to reduce and replace in vivo studies using bottom–up and top–down approaches
L Scott, C Eskes, S Hoffmann, E Adriaens, N Alepée, M Bufo, R Clothier, ...
Toxicology in Vitro 24 (1), 1-9, 2010
2012010
ECVAM retrospective validation of in vitro micronucleus test (MNT)
R Corvi, S Albertini, T Hartung, S Hoffmann, D Maurici, S Pfuhler, ...
Mutagenesis 23 (4), 271-283, 2008
1722008
Integrated Testing Strategies (ITS) for safety assessment.
C Rovida, N Alépée, AM Api, DA Basketter, F y Bois, F Caloni, E Corsini, ...
ALTEX-Alternatives to Animal Experimentations 32 (1), 25-40, 2015
1702015
Non-animal methods to predict skin sensitization (II): an assessment of defined approaches
NC Kleinstreuer, S Hoffmann, N Alépée, D Allen, T Ashikaga, W Casey, ...
Critical reviews in toxicology 48 (5), 359-374, 2018
1672018
Toward an evidence-based toxicology
S Hoffmann, T Hartung
Human & experimental toxicology 25 (9), 497-513, 2006
1592006
Non-animal methods to predict skin sensitization (I): the Cosmetics Europe database
S Hoffmann, N Kleinstreuer, N Alépée, D Allen, AM Api, T Ashikaga, ...
Critical reviews in toxicology 48 (5), 344-358, 2018
1512018
Systematic evaluation of non-animal test methods for skin sensitisation safety assessment
K Reisinger, S Hoffmann, N Alépée, T Ashikaga, J Barroso, C Elcombe, ...
Toxicology in Vitro 29 (1), 259-270, 2015
1512015
Food for thought... on in silico methods in toxicology
T Hartung, S Hoffmann
ALTEX-Alternatives to animal experimentation 26 (3), 155-166, 2009
1142009
Heterozygous toll-like receptor 4 polymorphism does not influence lipopolysaccharide-induced cytokine release in human whole blood
S Von Aulock, NWJ Schröder, K Gueinzius, S Traub, S Hoffmann, K Graf, ...
The Journal of infectious diseases 188 (6), 938-943, 2003
1042003
International validation of pyrogen tests based on cryopreserved human primary blood cells
S Schindler, I Spreitzer, B Löschner, S Hoffmann, K Hennes, M Halder, ...
Journal of immunological methods 316 (1-2), 42-51, 2006
1022006
Retrospective analysis of the Draize test for serious eye damage/eye irritation: importance of understanding the in vivo endpoints under UN GHS/EU CLP for the development and …
E Adriaens, J Barroso, C Eskes, S Hoffmann, P McNamee, N Alépée, ...
Archives of toxicology 88, 701-723, 2014
1012014
Food for thought... Mechanistic validation
T Hartung, S Hoffmann, M Stephens
Altex 30 (2), 119, 2013
892013
Implementing systematic review techniques in chemical risk assessment: Challenges, opportunities and recommendations
P Whaley, C Halsall, M Ågerstrand, E Aiassa, D Benford, G Bilotta, ...
Environment international 92, 556-564, 2016
862016
The principles of weight of evidence validation of test methods and testing strategies: The report and recommendations of ECVAM workshop 58
M Balls, P Amcoff, S Bremer, S Casati, S Coecke, R Clothier, R Combes, ...
Alternatives to laboratory animals 34 (6), 603-620, 2006
842006
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