A large-scale evaluation of computational protein function prediction P Radivojac, WT Clark, TR Oron, AM Schnoes, T Wittkop, A Sokolov, ... Nature methods 10 (3), 221-227, 2013 | 1088 | 2013 |
An expanded evaluation of protein function prediction methods shows an improvement in accuracy Y Jiang, TR Oron, WT Clark, AR Bankapur, D D’Andrea, R Lepore, ... Genome biology 17 (1), 1-19, 2016 | 425 | 2016 |
Testing the ortholog conjecture with comparative functional genomic data from mammals NL Nehrt, WT Clark, P Radivojac, MW Hahn PLoS computational biology 7 (6), e1002073, 2011 | 227 | 2011 |
An integrated approach to inferring gene–disease associations in humans P Radivojac, K Peng, WT Clark, BJ Peters, A Mohan, SM Boyle, ... Proteins: Structure, Function, and Bioinformatics 72 (3), 1030-1037, 2008 | 212 | 2008 |
Analysis of protein function and its prediction from amino acid sequence WT Clark, P Radivojac Proteins: Structure, Function, and Bioinformatics 79 (7), 2086-2096, 2011 | 173 | 2011 |
Information-theoretic evaluation of predicted ontological annotations WT Clark, P Radivojac Bioinformatics 29 (13), i53-i61, 2013 | 138 | 2013 |
Analysis of deletion breakpoints from 1,092 humans reveals details of mutation mechanisms A Abyzov, S Li, DR Kim, M Mohiyuddin, AM Stütz, NF Parrish, XJ Mu, ... Nature communications 6 (1), 1-12, 2015 | 97 | 2015 |
Comparative analysis of pseudogenes across three phyla C Sisu, B Pei, J Leng, A Frankish, Y Zhang, S Balasubramanian, R Harte, ... Proceedings of the National Academy of Sciences 111 (37), 13361-13366, 2014 | 88 | 2014 |
The impact of incomplete knowledge on the evaluation of protein function prediction: a structured-output learning perspective Y Jiang, WT Clark, I Friedberg, P Radivojac Bioinformatics 30 (17), i609-i616, 2014 | 47 | 2014 |
Using compression to identify classes of inauthentic texts MM Dalkilic, WT Clark, JC Costello, P Radivojac Proceedings of the 2006 SIAM International Conference on Data Mining, 604-608, 2006 | 37 | 2006 |
Prediction of functional regulatory SNPs in monogenic and complex disease Y Zhao, WT Clark, M Mort, DN Cooper, P Radivojac, SD Mooney Human mutation 32 (10), 1183-1190, 2011 | 30 | 2011 |
Characterization of glycan substrates accumulating in GM1 Gangliosidosis R Lawrence, JL Van Vleet, L Mangini, A Harris, N Martin, W Clark, ... Molecular genetics and metabolism reports 21, 100524, 2019 | 26 | 2019 |
Assessment of predicted enzymatic activity of α‐N‐acetylglucosaminidase variants of unknown significance for CAGI 2016 WT Clark, L Kasak, C Bakolitsa, Z Hu, G Andreoletti, G Babbi, Y Bromberg, ... Human mutation 40 (9), 1519-1529, 2019 | 17 | 2019 |
Identifying therapeutic drug targets using bidirectional effect genes K Estrada, S Froelich, A Wuster, CR Bauer, T Sterling, WT Clark, Y Ru, ... Nature Communications 12 (1), 1-11, 2021 | 16 | 2021 |
Utilizing ExAC to assess the hidden contribution of variants of unknown significance to Sanfilippo Type B incidence WT Clark, GK Yu, M Aoyagi-Scharber, JH LeBowitz Plos one 13 (7), e0200008, 2018 | 15 | 2018 |
From protein-disease associations to disease informatics MM Dalkilic, JC Costello, WT Clark, P Radivojac Front Biosci 13, 3391-3407, 2008 | 15 | 2008 |
Predicting disease severity in metachromatic leukodystrophy using protein activity and a patient phenotype matrix M Trinidad, X Hong, S Froelich, J Daiker, J Sacco, HP Nguyen, ... Genome Biology 24 (1), 172, 2023 | 9 | 2023 |
Vector quantization kernels for the classification of protein sequences and structures WT Clark, P Radivojac Biocomputing 2014, 316-327, 2014 | 9 | 2014 |
Identifying therapeutic drug targets for rare and common forms of short stature K Estrada, S Froelich, A Wuster, CR Bauer, T Sterling, WT Clark, Y Ru, ... bioRxiv, 2020 | 5 | 2020 |
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods Genome Interpretation Consortium arXiv e-prints, arXiv: 2205.05897, 2022 | 2 | 2022 |