Structural basis for the nucleotide-dependent dimerization of the large G protein atlastin-1/SPG3A LJ Byrnes, H Sondermann Proceedings of the National Academy of Sciences 108 (6), 2216-2221, 2011 | 201 | 2011 |
Structural basis for conformational switching and GTP loading of the large G protein atlastin LJ Byrnes, A Singh, K Szeto, NM Benvin, JP O'donnell, WR Zipfel, ... The EMBO journal 32 (3), 369-384, 2013 | 112 | 2013 |
The catalytic mechanism of cyclic GMP‐AMP synthase (cGAS) and implications for innate immunity and inhibition J Hall, EC Ralph, S Shanker, H Wang, LJ Byrnes, R Horst, J Wong, ... Protein Science 26 (12), 2367-2380, 2017 | 68 | 2017 |
The Crystal Structures of Substrate and Nucleotide Complexes of Enterococcus faecium Aminoglycoside-2′′-Phosphotransferase-IIa [APH(2′′)-IIa] Provide … PG Young, R Walanj, V Lakshmi, LJ Byrnes, P Metcalf, EN Baker, ... Journal of bacteriology 191 (13), 4133-4143, 2009 | 68 | 2009 |
Circular permutation of red fluorescent proteins B Shui, Q Wang, F Lee, LJ Byrnes, DM Chudakov, SA Lukyanov, ... PLoS One 6 (5), e20505, 2011 | 47 | 2011 |
Sites associated with Kalydeco binding on human cystic fibrosis transmembrane conductance regulator revealed by hydrogen/deuterium exchange LJ Byrnes, Y Xu, X Qiu, JD Hall, GM West Scientific Reports 8 (1), 4664, 2018 | 34 | 2018 |
Aminoglycoside 2′′-phosphotransferase IIIa (APH (2′′)-IIIa) Prefers GTP over ATP: structural templates for nucleotide recognition IN the bacterial AMINOGLYCOSIDE-2′′ kinases CA Smith, M Toth, H Frase, LJ Byrnes, SB Vakulenko Journal of Biological Chemistry 287 (16), 12893-12903, 2012 | 34 | 2012 |
Binding screen for cystic fibrosis transmembrane conductance regulator correctors finds new chemical matter and yields insights into cystic fibrosis therapeutic strategy JD Hall, H Wang, LJ Byrnes, S Shanker, K Wang, IV Efremov, PA Chong, ... Protein Science 25 (2), 360-373, 2016 | 32 | 2016 |
Versatile membrane deformation potential of activated pacsin SL Goh, Q Wang, LJ Byrnes, H Sondermann PLoS one 7 (12), e51628, 2012 | 30 | 2012 |
Molecular mechanism of a green-shifted, pH-dependent red fluorescent protein mKate variant Q Wang, LJ Byrnes, B Shui, UF Röhrig, A Singh, DM Chudakov, ... PloS one 6 (8), e23513, 2011 | 19 | 2011 |
A hereditary spastic paraplegia–associated atlastin variant exhibits defective allosteric coupling in the catalytic core JP O’Donnell, LJ Byrnes, RB Cooley, H Sondermann Journal of Biological Chemistry 293 (2), 687-700, 2018 | 15 | 2018 |
In vitro selection and analysis of SARS-CoV-2 nirmatrelvir resistance mutations contributing to clinical virus resistance surveillance Y Zhu, I Yurgelonis, S Noell, Q Yang, S Guan, Z Li, L Hao, H Rothan, ... Science advances 10 (30), eadl4013, 2024 | 9 | 2024 |
Species differences in plasma protein binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease inhibitor nirmatrelvir SR Greenfield, H Eng, Q Yang, C Guo, L Byrnes, A Dantonio, G West, L Di, ... Xenobiotica 53 (1), 12-24, 2023 | 6 | 2023 |
The hypervariable region of atlastin-1 is a site for intrinsic and extrinsic regulation CM Kelly, LJ Byrnes, N Neela, H Sondermann, JP O’Donnell Journal of Cell Biology 220 (11), 2021 | 4 | 2021 |
Purification, crystallization and preliminary X-ray analysis of aminoglycoside-2′′-phosphotransferase-Ic [APH (2′′)-Ic] from Enterococcus gallinarum LJ Byrnes, A Badarau, SB Vakulenko, CA Smith Acta Crystallographica Section F: Structural Biology and Crystallization …, 2008 | 3 | 2008 |
Discovery, Characterization, and Structure of a Cell Active PAD2 Inhibitor Acting through a Novel Allosteric Mechanism LJ Byrnes, WY Choi, P Balbo, ME Banker, J Chang, S Chen, X Cheng, ... ACS Chemical Biology 19 (10), 2186-2197, 2024 | | 2024 |
2324 From chaperonins to Rubisco assembly and metabolic repair Manajit Hayer-Hartl J Hall, EC Ralph, S Shanker, H Wang, LJ Byrnes, R Horst, J Wong, ... PROTEIN SCIENCE 26, 2323-2323, 2017 | | 2017 |
Aminoglycoside 2 inch-Phosphotransferase IIIa (APH (2-inch) IIIa) Prefers GTP over ATP Structural Templates for Nucleotide Recognition in the Bacterial Aminoglycoside-2 inch … CA Smith, M Toth, H Frase, LJ Byrnes, SB Vakulenko J. Biol. Chem. 287: 12893-12903, 2012, 2013 | | 2013 |
Molecular basis for nucleotide-dependent conformational changes of the large GTPase atlastin LJ Byrnes Cornell University, 2013 | | 2013 |
Crystallographic Studies of Two Bacterial AntibioticResistance Enzymes: Aminoglycoside Phosphotransferase (2')-Ic and GES-1\beta-lactamase L Brynes J. Undergrad. Stud., 2007 | | 2007 |