| Metformin is a potent inhibitor of endometrial cancer cell proliferation—implications for a novel treatment strategy LA Cantrell, C Zhou, A Mendivil, KM Malloy, PA Gehrig, VL Bae-Jump Gynecologic oncology 116 (1), 92-98, 2010 | 442 | 2010 |
| Glucose promotes cell proliferation, glucose uptake and invasion in endometrial cancer cells via AMPK/mTOR/S6 and MAPK signaling J Han, L Zhang, H Guo, WZ Wysham, DR Roque, AK Willson, X Sheng, ... Gynecologic oncology 138 (3), 668-675, 2015 | 183 | 2015 |
| Metformin potentiates the effects of paclitaxel in endometrial cancer cells through inhibition of cell proliferation and modulation of the mTOR pathway RK Hanna, C Zhou, KM Malloy, L Sun, Y Zhong, PA Gehrig, VL Bae-Jump Gynecologic oncology 125 (2), 458-469, 2012 | 179 | 2012 |
| Glutamine promotes ovarian cancer cell proliferation through the mTOR/S6 pathway L Yuan, X Sheng, AK Willson, DR Roque, JE Stine, H Guo, HM Jones, ... Endocrine-related cancer 22 (4), 577-591, 2015 | 103 | 2015 |
| Rapamycin potentiates the effects of paclitaxel in endometrial cancer cells through inhibition of cell proliferation and induction of apoptosis A Shafer, C Zhou, PA Gehrig, JF Boggess, VL Bae‐Jump International journal of cancer 126 (5), 1144-1154, 2010 | 98 | 2010 |
| JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer H Qiu, AL Jackson, JE Kilgore, Y Zhong, LLY Chan, PA Gehrig, C Zhou, ... Oncotarget 6 (9), 6915, 2015 | 94 | 2015 |
| Rapamycin Inhibits Telomerase Activity by Decreasing the hTERT mRNA Level in Endometrial Cancer Cells C Zhou, PA Gehrig, YE Whang, JF Boggess Molecular cancer therapeutics 2 (8), 789-795, 2003 | 91 | 2003 |
| Simvastatin, an HMG-CoA reductase inhibitor, exhibits anti-metastatic and anti-tumorigenic effects in endometrial cancer MN Schointuch, TP Gilliam, JE Stine, X Han, C Zhou, PA Gehrig, K Kim, ... Gynecologic oncology 134 (2), 346-355, 2014 | 85 | 2014 |
| The HMG-CoA reductase inhibitor, simvastatin, exhibits anti-metastatic and anti-tumorigenic effects in ovarian cancer JE Stine, H Guo, X Sheng, X Han, MN Schointuch, TP Gilliam, PA Gehrig, ... Oncotarget 7 (1), 946, 2016 | 80 | 2016 |
| Synergistic effect of rapamycin and cisplatin in endometrial cancer cells VL Bae‐Jump, C Zhou, JF Boggess, PA Gehrig Cancer: Interdisciplinary International Journal of the American Cancer …, 2009 | 79 | 2009 |
| Glutaminase inhibitor compound 968 inhibits cell proliferation and sensitizes paclitaxel in ovarian cancer L Yuan, X Sheng, LH Clark, L Zhang, H Guo, HM Jones, AK Willson, ... American journal of translational research 8 (10), 4265, 2016 | 76 | 2016 |
| The PTEN tumor suppressor inhibits telomerase activity in endometrial cancer cells by decreasing hTERT mRNA levels C Zhou, VL Bae-Jump, YE Whang, PA Gehrig, JF Boggess Gynecologic oncology 101 (2), 305-310, 2006 | 68 | 2006 |
| Atorvastatin exhibits anti-tumorigenic and anti-metastatic effects in ovarian cancer in vitro HM Jones, Z Fang, W Sun, LH Clark, JE Stine, AQ Tran, SA Sullivan, ... American journal of cancer research 7 (12), 2478, 2017 | 64 | 2017 |
| Estrogen induction of telomerase activity through regulation of the mitogen-activated protein kinase (MAPK) dependent pathway in human endometrial cancer cells C Zhou, TA Steplowski, HK Dickens, KM Malloy, PA Gehrig, JF Boggess, ... PloS one 8 (2), e55730, 2013 | 62 | 2013 |
| Obesity increases tumor aggressiveness in a genetically engineered mouse model of serous ovarian cancer L Makowski, C Zhou, Y Zhong, PF Kuan, C Fan, BP Sampey, M Difurio, ... Gynecologic oncology 133 (1), 90-97, 2014 | 61 | 2014 |
| Biological role of matrix stiffness in tumor growth and treatment B Deng, Z Zhao, W Kong, C Han, X Shen, C Zhou Journal of translational medicine 20 (1), 540, 2022 | 60 | 2022 |
| JQ1 suppresses tumor growth via PTEN/PI3K/AKT pathway in endometrial cancer H Qiu, J Li, LH Clark, AL Jackson, L Zhang, H Guo, JE Kilgore, PA Gehrig, ... Oncotarget 7 (41), 66809, 2016 | 56 | 2016 |
| Evaluation of the antitumor effects of c-Myc-Max heterodimerization inhibitor 100258-F4 in ovarian cancer cells J Wang, X Ma, HM Jones, LLY Chan, F Song, W Zhang, VL Bae-Jump, ... Journal of translational medicine 12, 1-11, 2014 | 54 | 2014 |
| Estrogen-receptor-dependent regulation of telomerase activity in human endometrial cancer cell lines JF Boggess, C Zhou, VL Bae-Jump, PA Gehrig, YE Whang Gynecologic oncology 103 (2), 417-424, 2006 | 54 | 2006 |
| Reversal of obesity-driven aggressiveness of endometrial cancer by metformin H Guo, W Kong, L Zhang, J Han, LH Clark, Y Yin, Z Fang, W Sun, J Wang, ... American journal of cancer research 9 (10), 2170, 2019 | 52 | 2019 |
Varun Vijay PrabhuSenior Director R&D, ChimerixVerified email at chimerix.com
