Strategies to increase drug penetration in solid tumors IK Choi, R Strauss, M Richter, CO Yun, A Lieber Frontiers in oncology 3, 193, 2013 | 181 | 2013 |
Enhanced antitumor effect of oncolytic adenovirus expressing interleukin-12 and B7-1 in an immunocompetent murine model YS Lee, JH Kim, KJ Choi, IK Choi, H Kim, S Cho, BC Cho, CO Yun Clinical cancer research 12 (19), 5859-5868, 2006 | 178 | 2006 |
Therapeutic and tumor-specific immunity induced by combination of dendritic cells and oncolytic adenovirus expressing IL-12 and 4-1BBL JH Huang, SN Zhang, KJ Choi, IK Choi, JH Kim, M Lee, H Kim, CO Yun Molecular Therapy 18 (2), 264-274, 2010 | 136 | 2010 |
Oncolytic adenovirus co-expressing IL-12 and IL-18 improves tumor-specific immunity via differentiation of T cells expressing IL-12Rβ2 or IL-18Rα IK Choi, JS Lee, SN Zhang, J Park, KM Lee, CH Sonn, CO Yun Gene therapy 18 (9), 898-909, 2011 | 129 | 2011 |
Effect of decorin on overcoming the extracellular matrix barrier for oncolytic virotherapy IK Choi, YS Lee, JY Yoo, AR Yoon, H Kim, DS Kim, DG Seidler, JH Kim, ... Gene therapy 17 (2), 190-201, 2010 | 115 | 2010 |
Optimizing DC vaccination by combination with oncolytic adenovirus coexpressing IL-12 and GM-CSF SN Zhang, IK Choi, JH Huang, JY Yoo, KJ Choi, CO Yun Molecular Therapy 19 (8), 1558-1568, 2011 | 107 | 2011 |
Strengthening of antitumor immune memory and prevention of thymic atrophy mediated by adenovirus expressing IL-12 and GM-CSF KJ Choi, SN Zhang, IK Choi, JS Kim, CO Yun Gene therapy 19 (7), 711-723, 2012 | 83 | 2012 |
Identification and functional characterization of nuclear mortalin in human carcinogenesis J Ryu, Z Kaul, AR Yoon, Y Liu, T Yaguchi, Y Na, HM Ahn, R Gao, IK Choi, ... Journal of Biological Chemistry 289 (36), 24832-24844, 2014 | 73 | 2014 |
Ex vivo expansion of highly cytotoxic human NK cells by cocultivation with irradiated tumor cells for adoptive immunotherapy SA Lim, TJ Kim, JE Lee, CH Sonn, K Kim, J Kim, JG Choi, IK Choi, ... Cancer research 73 (8), 2598-2607, 2013 | 69 | 2013 |
Oncolytic adenovirus coexpressing interleukin-12 and decorin overcomes Treg-mediated immunosuppression inducing potent antitumor effects in a weakly immunogenic tumor model E Oh, IK Choi, JW Hong, CO Yun Oncotarget 8 (3), 4730, 2017 | 65 | 2017 |
Signaling by the Epstein–Barr virus LMP1 protein induces potent cytotoxic CD4+ and CD8+ T cell responses IK Choi, Z Wang, Q Ke, M Hong, Y Qian, X Zhao, Y Liu, HJ Kim, J Ritz, ... Proceedings of the National Academy of Sciences 115 (4), E686-E695, 2018 | 62 | 2018 |
Oncolytic adenovirus expressing relaxin (YDC002) enhances therapeutic efficacy of gemcitabine against pancreatic cancer KH Jung, IK Choi, HS Lee, HH Yan, MK Son, HM Ahn, JW Hong, CO Yun, ... Cancer Letters 396, 155-166, 2017 | 62 | 2017 |
Oncolytic adenovirus expressing IL-23 and p35 elicits IFN-γ-and TNF-α-co-producing T cell-mediated antitumor immunity IK Choi, Y Li, E Oh, J Kim, CO Yun PloS one 8 (7), e67512, 2013 | 59 | 2013 |
Recent developments in oncolytic adenovirus-based immunotherapeutic agents for use against metastatic cancers IK Choi, CO Yun Cancer gene therapy 20 (2), 70-76, 2013 | 58 | 2013 |
Mechanism of EBV inducing anti-tumour immunity and its therapeutic use IK Choi, Z Wang, Q Ke, M Hong, DW Paul, SM Fernandes, Z Hu, ... Nature 590 (7844), 157-162, 2021 | 55 | 2021 |
MicroRNA-296 is enriched in cancer cells and downregulates p21WAF1 mRNA expression via interaction with its 3′ untranslated region A Yoon, R Gao, Z Kaul, IK Choi, J Ryu, JR Noble, Y Kato, S Saito, ... Nucleic acids research 39 (18), 8078-8091, 2011 | 55 | 2011 |
Quantitative impact of immunomodulation versus oncolysis with cytokine-expressing virus therapeutics PS Kim, JJ Crivelli, IK Choi, CO Yun, JR Wares Mathematical Biosciences & Engineering 12 (4), 841, 2015 | 49 | 2015 |
A novel three‐dimensional model system for keloid study: Organotypic multicellular scar model WJ Lee, IK Choi, JH Lee, YO Kim, CO Yun Wound Repair and Regeneration 21 (1), 155-165, 2013 | 44 | 2013 |
Decorin‐expressing adenovirus decreases collagen synthesis and upregulates MMP expression in keloid fibroblasts and keloid spheroids WJ Lee, HM Ahn, H Roh, Y Na, IK Choi, JH Lee, YO Kim, DH Lew, ... Experimental dermatology 24 (8), 591-597, 2015 | 41 | 2015 |
Proproliferative functions of Drosophila small mitochondrial heat shock protein 22 in human cells R Wadhwa, J Ryu, R Gao, IK Choi, G Morrow, K Kaur, I Kim, SC Kaul, ... Journal of Biological Chemistry 285 (6), 3833-3839, 2010 | 41 | 2010 |